Sparsomycin Exhibits Potent Antiplasmodial Activity In Vitro and In Vivo

The emerging spread of drug-resistant malaria parasites highlights the need for new antimalarial agents. This study evaluated the growth-inhibitory effects of sparsomycin (Sm), a peptidyl transferase inhibitor, against Plasmodium falciparum 3D7 (chloroquine-sensitive strain), P. falciparum K1 (resis...

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Detalles Bibliográficos
Autores principales: Ariefta, Nanang Rudianto, Pagmadulam, Baldorj, Nihei, Coh-ichi, Nishikawa, Yoshifumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8954220/
https://www.ncbi.nlm.nih.gov/pubmed/35335918
http://dx.doi.org/10.3390/pharmaceutics14030544

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8954220/
https://www.ncbi.nlm.nih.gov/pubmed/35335918
http://dx.doi.org/10.3390/pharmaceutics14030544

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