Intracerebral but Not Peripheral Infection of Live Porphyromonas gingivalis Exacerbates Alzheimer’s Disease Like Amyloid Pathology in APP-TgCRND8 Mice

The impact of oral microbial dysbiosis on Alzheimer’s disease (AD) remains controversial. Building off recent studies reporting that various microbes might directly seed or promote amyloid β (Aβ) deposition, we evaluated the effects of periodontal bacteria (Porphyromonas gingivalis, Treponema dentic...

Descripción completa

Detalles Bibliográficos
Autores principales: Aravindraja, Chairmandurai, Sakthivel, Ravi, Liu, Xuefei, Goodwin, Marshall, Veena, Patnam, Godovikova, Valentina, Fenno, J. Christopher, Levites, Yona, Golde, Todd E., Kesavalu, Lakshmyya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8954230/
https://www.ncbi.nlm.nih.gov/pubmed/35328748
http://dx.doi.org/10.3390/ijms23063328

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8954230/
https://www.ncbi.nlm.nih.gov/pubmed/35328748
http://dx.doi.org/10.3390/ijms23063328

Ejemplares similares