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Intracerebral but Not Peripheral Infection of Live Porphyromonas gingivalis Exacerbates Alzheimer’s Disease Like Amyloid Pathology in APP-TgCRND8 Mice
The impact of oral microbial dysbiosis on Alzheimer’s disease (AD) remains controversial. Building off recent studies reporting that various microbes might directly seed or promote amyloid β (Aβ) deposition, we evaluated the effects of periodontal bacteria (Porphyromonas gingivalis, Treponema dentic...
Autores principales: | Aravindraja, Chairmandurai, Sakthivel, Ravi, Liu, Xuefei, Goodwin, Marshall, Veena, Patnam, Godovikova, Valentina, Fenno, J. Christopher, Levites, Yona, Golde, Todd E., Kesavalu, Lakshmyya |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8954230/ https://www.ncbi.nlm.nih.gov/pubmed/35328748 http://dx.doi.org/10.3390/ijms23063328 |
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