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Structural Plasticity Is a Feature of Rheostat Positions in the Human Na(+)/Taurocholate Cotransporting Polypeptide (NTCP)
In the Na(+)/taurocholate cotransporting polypeptide (NTCP), the clinically relevant S267F polymorphism occurs at a “rheostat position”. That is, amino acid substitutions at this position (“S267X”) lead to a wide range of functional outcomes. This result was particularly striking because molecular m...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8954283/ https://www.ncbi.nlm.nih.gov/pubmed/35328632 http://dx.doi.org/10.3390/ijms23063211 |