Loss of Microglial Insulin Receptor Leads to Sex-Dependent Metabolic Disorders in Obese Mice

Obesity and type 2 diabetes mellitus (T2DM) are highly prevalent disorders, associated with insulin resistance and chronic inflammation. The brain is key for energy homeostasis and contains many insulin receptors. Microglia, the resident brain immune cells, are known to express insulin receptors (In...

Descripción completa

Detalles Bibliográficos
Autores principales: Milanova, Irina V., Korpel, Nikita L., Correa-da-Silva, Felipe, Berends, Eline, Osman, Samar, la Fleur, Susanne E., Fliers, Eric, Kalsbeek, Andries, Yi, Chun-Xia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8954452/
https://www.ncbi.nlm.nih.gov/pubmed/35328354
http://dx.doi.org/10.3390/ijms23062933

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8954452/
https://www.ncbi.nlm.nih.gov/pubmed/35328354
http://dx.doi.org/10.3390/ijms23062933

Ejemplares similares