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Canrenone Restores Vasorelaxation Impaired by Marinobufagenin in Human Preeclampsia

Previous studies implicated cardiotonic steroids, including Na/K-ATPase inhibitor marinobufagenin (MBG), in the pathogenesis of preeclampsia (PE). Recently, we demonstrated that (i) MBG induces fibrosis in rat tissues via a mechanism involving Fli1, a negative regulator of collagen-1 synthesis, and...

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Detalles Bibliográficos
Autores principales: Agalakova, Natalia I., Grigorova, Yulia N., Ershov, Ivan A., Reznik, Vitaly A., Mikhailova, Elena V., Nadei, Olga V., Samuilovskaya, Leticia, Romanova, Larisa A., Adair, C. David, Romanova, Irina V., Bagrov, Alexei Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8954517/
https://www.ncbi.nlm.nih.gov/pubmed/35328757
http://dx.doi.org/10.3390/ijms23063336