Cargando…
Canrenone Restores Vasorelaxation Impaired by Marinobufagenin in Human Preeclampsia
Previous studies implicated cardiotonic steroids, including Na/K-ATPase inhibitor marinobufagenin (MBG), in the pathogenesis of preeclampsia (PE). Recently, we demonstrated that (i) MBG induces fibrosis in rat tissues via a mechanism involving Fli1, a negative regulator of collagen-1 synthesis, and...
Autores principales: | Agalakova, Natalia I., Grigorova, Yulia N., Ershov, Ivan A., Reznik, Vitaly A., Mikhailova, Elena V., Nadei, Olga V., Samuilovskaya, Leticia, Romanova, Larisa A., Adair, C. David, Romanova, Irina V., Bagrov, Alexei Y. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8954517/ https://www.ncbi.nlm.nih.gov/pubmed/35328757 http://dx.doi.org/10.3390/ijms23063336 |
Ejemplares similares
-
Antibody to Marinobufagenin Reverses Placenta-Induced Fibrosis of Umbilical Arteries in Preeclampsia
por: Fedorova, Olga V., et al.
Publicado: (2018) -
Fli1 and Tissue Fibrosis in Various Diseases
por: Mikhailova, Elena V., et al.
Publicado: (2023) -
Endogenous Bufadienolides, Fibrosis and Preeclampsia
por: Reznik, Vitaliy A., et al.
Publicado: (2019) -
Dietary Sodium Restriction Reduces Arterial Stiffness, Vascular TGF-β-Dependent Fibrosis and Marinobufagenin in Young Normotensive Rats
por: Grigorova, Yulia N., et al.
Publicado: (2018) -
Effect of Cardiotonic Steroid Marinobufagenin on Vascular Remodeling and Cognitive Impairment in Young Dahl-S Rats
por: Grigorova, Yulia N., et al.
Publicado: (2022)