Physicochemical Profile of Antiandrogen Drug Bicalutamide: Solubility, Distribution, Permeability

The pharmacologically relevant physicochemical properties of the antiandrogen drug bicalutamide (BCL) have been determined for the first time. Solubility in aqueous solution, 1-octanol, n-hexane, and ethanol was measured by the shake flask method in the temperature range of 293.15–313.15 K. The comp...

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Detalles Bibliográficos
Autores principales: Volkova, Tatyana V., Simonova, Olga R., Perlovich, German L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8954523/
https://www.ncbi.nlm.nih.gov/pubmed/35336047
http://dx.doi.org/10.3390/pharmaceutics14030674

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8954523/
https://www.ncbi.nlm.nih.gov/pubmed/35336047
http://dx.doi.org/10.3390/pharmaceutics14030674

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