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Physicochemical Profile of Antiandrogen Drug Bicalutamide: Solubility, Distribution, Permeability
The pharmacologically relevant physicochemical properties of the antiandrogen drug bicalutamide (BCL) have been determined for the first time. Solubility in aqueous solution, 1-octanol, n-hexane, and ethanol was measured by the shake flask method in the temperature range of 293.15–313.15 K. The comp...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8954523/ https://www.ncbi.nlm.nih.gov/pubmed/35336047 http://dx.doi.org/10.3390/pharmaceutics14030674 |