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Alternative Promoters of GRIK2 (GluR6) Gene in Human Carcinoma Cell Lines Are Regulated by Differential Methylation of CpG Dinucleotides

The ionotropic glutamate receptor 6 (GluR6 or GRIK2) gene is transcribed by two cell-type-specific promoters in neuronal and non-neuronal cells, which results in five different transcript variants. The purpose of this study was to explore cell-type-specific silencing of these promoters by epigenetic...

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Detalles Bibliográficos
Autores principales: Zhawar, Vikramjit K., Kandpal, Raj P., Athwal, Raghbir S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8954616/
https://www.ncbi.nlm.nih.gov/pubmed/35328043
http://dx.doi.org/10.3390/genes13030490