Discovery of Novel Trace Amine-Associated Receptor 5 (TAAR5) Antagonists Using a Deep Convolutional Neural Network

Trace amine-associated receptor 5 (TAAR5) is a G protein-coupled receptor that belongs to the TAARs family (TAAR1-TAAR9). TAAR5 is expressed in the olfactory epithelium and is responsible for sensing 3-methylamine (TMA). However, recent studies showed that TAAR5 is also expressed in the limbic brain...

Descripción completa

Detalles Bibliográficos
Autores principales: Bon, Carlotta, Chern, Ting-Rong, Cichero, Elena, O’Brien, Terrence E., Gustincich, Stefano, Gainetdinov, Raul R., Espinoza, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8954676/
https://www.ncbi.nlm.nih.gov/pubmed/35328548
http://dx.doi.org/10.3390/ijms23063127

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8954676/
https://www.ncbi.nlm.nih.gov/pubmed/35328548
http://dx.doi.org/10.3390/ijms23063127

Ejemplares similares