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Discovery of Novel Trace Amine-Associated Receptor 5 (TAAR5) Antagonists Using a Deep Convolutional Neural Network

Trace amine-associated receptor 5 (TAAR5) is a G protein-coupled receptor that belongs to the TAARs family (TAAR1-TAAR9). TAAR5 is expressed in the olfactory epithelium and is responsible for sensing 3-methylamine (TMA). However, recent studies showed that TAAR5 is also expressed in the limbic brain...

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Detalles Bibliográficos
Autores principales:	Bon, Carlotta, Chern, Ting-Rong, Cichero, Elena, O’Brien, Terrence E., Gustincich, Stefano, Gainetdinov, Raul R., Espinoza, Stefano
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8954676/ https://www.ncbi.nlm.nih.gov/pubmed/35328548 http://dx.doi.org/10.3390/ijms23063127

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