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Notch Signaling and Cross-Talk in Hypoxia: A Candidate Pathway for High-Altitude Adaptation

Hypoxia triggers complex inter- and intracellular signals that regulate tissue oxygen (O(2)) homeostasis, adjusting convective O(2) delivery and utilization (i.e., metabolism). Human populations have been exposed to high-altitude hypoxia for thousands of years and, in doing so, have undergone natura...

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Detalles Bibliográficos
Autores principales: O’Brien, Katie A., Murray, Andrew J., Simonson, Tatum S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8954738/
https://www.ncbi.nlm.nih.gov/pubmed/35330188
http://dx.doi.org/10.3390/life12030437