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Clathrate Hydrates of Organic Solvents as Auxiliary Intermediates in Pharmaceutical Research and Development: Improving Dissolution Behaviour of a New Anti-Tuberculosis Drug, Perchlozon

There is an urgent need for new drugs to overcome the challenge of the ever-growing drug resistance towards tuberculosis. A new, highly efficient anti-tuberculosis drug, Perchlozone (thioureidoiminomethylpyridinium perchlorate, Pz), is only available in an oral dosage form, though injectable forms a...

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Detalles Bibliográficos
Autores principales: Ogienko, Andrey G., Myz, Svetlana A., Nefedov, Andrey A., Ogienko, Anna A., Adamova, Tatyana P., Voronkova, Olga M., Amosova, Svetlana V., Trofimov, Boris A., Boldyrev, Vladimir V., Boldyreva, Elena V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8954777/
https://www.ncbi.nlm.nih.gov/pubmed/35335870
http://dx.doi.org/10.3390/pharmaceutics14030495