A Microphysiological Cell-Culturing System for Pharmacokinetic Drug Exposure and High-Resolution Imaging of Arrays of 3D Microtissues

Understanding the pharmacokinetic/pharmacodynamic (PK/PD)-relationship of a drug candidate is key to determine effective, yet safe treatment regimens for patients. However, current testing strategies are inefficient in characterizing in vivo responses to fluctuating drug concentrations during multi-...

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Detalles Bibliográficos
Autores principales: Lohasz, Christian, Loretan, Jacqueline, Sterker, Dario, Görlach, Ekkehard, Renggli, Kasper, Argast, Paul, Frey, Olivier, Wiesmann, Marion, Wartmann, Markus, Rausch, Martin, Hierlemann, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8954798/
https://www.ncbi.nlm.nih.gov/pubmed/35342386
http://dx.doi.org/10.3389/fphar.2021.785851

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8954798/
https://www.ncbi.nlm.nih.gov/pubmed/35342386
http://dx.doi.org/10.3389/fphar.2021.785851

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