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Transport of Prions in the Peripheral Nervous System: Pathways, Cell Types, and Mechanisms
Prion diseases are transmissible protein misfolding disorders that occur in animals and humans where the endogenous prion protein, PrP(C), undergoes a conformational change into self-templating aggregates termed PrP(Sc). Formation of PrP(Sc) in the central nervous system (CNS) leads to gliosis, spon...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8954800/ https://www.ncbi.nlm.nih.gov/pubmed/35337037 http://dx.doi.org/10.3390/v14030630 |