Quantitative Analysis of Daporinad (FK866) and Its In Vitro and In Vivo Metabolite Identification Using Liquid Chromatography-Quadrupole-Time-of-Flight Mass Spectrometry

Daporinad (FK866) is one of the highly specific inhibitors of nicotinamide phosphoribosyl transferase (NAMPT) and known to have its unique mechanism of action that induces the tumor cell apoptosis. In this study, a simple and sensitive liquid chromatography–quadrupole-time-of-flight–mass spectrometr...

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Detalles Bibliográficos
Autores principales: Park, Minjae, Lee, Byeong Ill, Choi, Jangmi, Park, Yuri, Park, Seo-Jin, Lim, Jeong-Hyeon, Lee, Jiyu, Shin, Young G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8954816/
https://www.ncbi.nlm.nih.gov/pubmed/35335372
http://dx.doi.org/10.3390/molecules27062011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8954816/
https://www.ncbi.nlm.nih.gov/pubmed/35335372
http://dx.doi.org/10.3390/molecules27062011

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