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Molecular Signaling Mechanisms for the Antidepressant Effects of NLX-101, a Selective Cortical 5-HT(1A) Receptor Biased Agonist

Depression is the most prevalent of the mental illnesses and serotonin (5-hydroxytryptamine, 5-HT) is considered to be the major neurotransmitter involved in its etiology and treatment. In this context, 5-HT(1A) receptors have attracted interest as targets for therapeutic intervention. Notably the a...

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Detalles Bibliográficos
Autores principales: Cabanu, Sharon, Pilar-Cuéllar, Fuencisla, Zubakina, Paula, Florensa-Zanuy, Eva, Senserrich, Júlia, Newman-Tancredi, Adrian, Adell, Albert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8954942/
https://www.ncbi.nlm.nih.gov/pubmed/35337135
http://dx.doi.org/10.3390/ph15030337