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Arene Ru(II) Complexes with Difluorinated Ligands Act as Potential Inducers of S-Phase Arrest via the Stabilization of c-myc G-Quadruplex DNA

Here, a series of half-sandwich arene Ru(II) complexes with difluorinated ligands [Ru(η(6)-arene)(L)Cl] (L(1) = 2-(2,3-difluorophenyl)imidazole[4,5f][1,10]-phenanthroline; L(2) = 2-(2,4-difluorophenyl)imidazole[4,5f][1,10]-phenanthroline; arene = benzene, toluene, and p-cymene) were synthesized and...

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Detalles Bibliográficos
Autores principales: Zeng, Liang, Yuan, Chanling, Shu, Jing, Qian, Jiayi, Wu, Qiong, Chen, Yanhua, Wu, Ruzhen, Ouyang, Xiaoming, Li, Yuan, Mei, Wenjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8954944/
https://www.ncbi.nlm.nih.gov/pubmed/35335261
http://dx.doi.org/10.3390/molecules27061897