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Depletion of transmembrane mucin 4 (Muc4) alters intestinal homeostasis in a genetically engineered mouse model of colorectal cancer

Mucins are components of the mucus layer overlying the intestinal epithelial cells, which maintains physiological homeostasis. Altered mucin expression is associated with disease progression. Expression of MUC4 decreases in colorectal cancer (CRC); however, its functional role and implications in th...

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Detalles Bibliográficos
Autores principales: Pothuraju, Ramesh, Pai, Priya, Chaudhary, Sanjib, Siddiqui, Jawed A., Cox, Jesse L., Kaur, Sukhwinder, Rachagani, Satyanarayana, Roy, Hemant K., Bouvet, Michael, Batra, Surinder K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8954958/
https://www.ncbi.nlm.nih.gov/pubmed/35255004
http://dx.doi.org/10.18632/aging.203935