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Depletion of transmembrane mucin 4 (Muc4) alters intestinal homeostasis in a genetically engineered mouse model of colorectal cancer
Mucins are components of the mucus layer overlying the intestinal epithelial cells, which maintains physiological homeostasis. Altered mucin expression is associated with disease progression. Expression of MUC4 decreases in colorectal cancer (CRC); however, its functional role and implications in th...
Autores principales: | Pothuraju, Ramesh, Pai, Priya, Chaudhary, Sanjib, Siddiqui, Jawed A., Cox, Jesse L., Kaur, Sukhwinder, Rachagani, Satyanarayana, Roy, Hemant K., Bouvet, Michael, Batra, Surinder K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8954958/ https://www.ncbi.nlm.nih.gov/pubmed/35255004 http://dx.doi.org/10.18632/aging.203935 |
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