Cell immortalization facilitates prelamin A clearance by increasing both cell proliferation and autophagic flux

Hutchinson-Gilford Progeria Syndrome is an ultrarare disease which is characterized by an accelerated senescence phenotype with deleterious consequences to people suffering this pathology. The production of an abnormal protein derived from lamin A, called progerin, presents a farnesylated domain, wh...

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Detalles Bibliográficos
Autores principales: González-Blanco, Carlos, Marqués, Patricia, Burillo, Jesús, Jiménez, Beatriz, García, Gema, Benito, Manuel, Guillén, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2022
Materias:
Priority Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8954962/
https://www.ncbi.nlm.nih.gov/pubmed/35306483
http://dx.doi.org/10.18632/aging.203943

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8954962/
https://www.ncbi.nlm.nih.gov/pubmed/35306483
http://dx.doi.org/10.18632/aging.203943

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