Cargando…

Modulation of RNA splicing associated with Wnt signaling pathway using FD-895 and pladienolide B

Alterations in RNA splicing are associated with different malignancies, including leukemia, lymphoma, and solid tumors. The RNA splicing modulators such as FD-895 and pladienolide B have been investigated in different malignancies to target/modulate spliceosome for therapeutic purpose. Different cel...

Descripción completa

Detalles Bibliográficos
Autores principales: Kumar, Deepak, Kashyap, Manoj K., Yu, Zhe, Spaanderman, Ide, Villa, Reymundo, Kipps, Thomas J., La Clair, James J., Burkart, Michael D., Castro, Januario E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8954975/
https://www.ncbi.nlm.nih.gov/pubmed/35230971
http://dx.doi.org/10.18632/aging.203924