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Glucose Metabolism and Aging of Hematopoietic Stem and Progenitor Cells

Comprehensive proteomics studies of human hematopoietic stem and progenitor cells (HSPC) have revealed that aging of the HSPC compartment is characterized by elevated glycolysis. This is in addition to deregulations found in murine transcriptomics studies, such as an increased differentiation bias t...

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Detalles Bibliográficos
Autores principales: Poisa-Beiro, Laura, Landry, Jonathan J. M., Raffel, Simon, Tanaka, Motomu, Zaugg, Judith, Gavin, Anne-Claude, Ho, Anthony D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8955027/
https://www.ncbi.nlm.nih.gov/pubmed/35328449
http://dx.doi.org/10.3390/ijms23063028