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New 1,3,4-Thiadiazole Derivatives with Anticancer Activity

We designed and synthesized the 1,3,4-thiadiazole derivatives differing in the structure of the substituents in C2 and C5 positions. The cytotoxic activity of the obtained compounds was then determined in biological studies using MCF-7 and MDA-MB-231 breast cancer cells and normal cell line (fibrobl...

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Detalles Bibliográficos
Autores principales: Janowska, Sara, Khylyuk, Dmytro, Bielawska, Anna, Szymanowska, Anna, Gornowicz, Agnieszka, Bielawski, Krzysztof, Noworól, Jarosław, Mandziuk, Sławomir, Wujec, Monika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8955053/
https://www.ncbi.nlm.nih.gov/pubmed/35335177
http://dx.doi.org/10.3390/molecules27061814