Pharmacokinetic Variability in Pre-Clinical Studies: Sample Study with Abiraterone in Rats and Implications for Short-Term Comparative Pharmacokinetic Study Designs

One of the major concerns for all in vivo experiments is intra- and inter-subject variability, which can be a great source of inaccuracy. The aim of this study is, therefore, to estimate the ability of parallel vs. cross-over design studies in order to describe the relative pharmacokinetic performan...

Descripción completa

Detalles Bibliográficos
Autores principales: Královičová, Jana, Bartůněk, Aleš, Hofmann, Jiří, Křížek, Tomáš, Kozlík, Petr, Roušarová, Jaroslava, Ryšánek, Pavel, Šíma, Martin, Slanař, Ondřej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8955109/
https://www.ncbi.nlm.nih.gov/pubmed/35336017
http://dx.doi.org/10.3390/pharmaceutics14030643

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8955109/
https://www.ncbi.nlm.nih.gov/pubmed/35336017
http://dx.doi.org/10.3390/pharmaceutics14030643

Ejemplares similares