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In Vitro Analysis of Biological Activity of Circulating Cell-Free DNA Isolated from Blood Plasma of Schizophrenic Patients and Healthy Controls

Schizophrenia is associated with low-grade systemic inflammation. Circulating cell-free DNA (c-cfDNA) belongs to the DAMP class. The major research question was: can the c-cfDNA of schizophrenic patients (sz-cfDNA) stimulate the DNA sensor genes, which control the innate immunity? We investigated th...

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Detalles Bibliográficos
Autores principales: Ershova, Elizaveta S., Shmarina, Galina V., Porokhovnik, Lev N., Zakharova, Natalia V., Kostyuk, George P., Umriukhin, Pavel E., Kutsev, Sergey I., Sergeeva, Vasilina A., Veiko, Natalia N., Kostyuk, Svetlana V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8955124/
https://www.ncbi.nlm.nih.gov/pubmed/35328103
http://dx.doi.org/10.3390/genes13030551