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A Novel Method to Reduce ELISA Serial Dilution Assay Workload Applied to SARS-CoV-2 and Seasonal HCoVs

Assays using ELISA measurements on serially diluted serum samples have been heavily used to measure serum reactivity to SARS-CoV-2 antigens and are widely used in virology and elsewhere in biology. We test a method using Bayesian hierarchical modelling to reduce the workload of these assays and meas...

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Detalles Bibliográficos
Autores principales: Pattinson, David, Jester, Peter, Guan, Lizheng, Yamayoshi, Seiya, Chiba, Shiho, Presler, Robert, Rao, Hongyu, Iwatsuki-Horimoto, Kiyoko, Ikeda, Nobuhiro, Hagihara, Masao, Uchida, Tomoyuki, Mitamura, Keiko, Halfmann, Peter, Neumann, Gabriele, Kawaoka, Yoshihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8955134/
https://www.ncbi.nlm.nih.gov/pubmed/35336970
http://dx.doi.org/10.3390/v14030562