Development and Evaluation of Nanoparticles-in-Film Technology to Achieve Extended In Vivo Exposure of MK-2048 for HIV Prevention

MK-2048 is a second-generation integrase inhibitor active against HIV, which has been applied vaginally using ring formulations. In this work, a nanoparticle-in-film technology was developed as a discrete pre-exposure prophylactic product option against HIV for an extended duration of use. A film pl...

Descripción completa

Detalles Bibliográficos
Autores principales: Tong, Xin, Patel, Sravan Kumar, Li, Jing, Patton, Dorothy, Xu, Elaine, Anderson, Peter L., Parikh, Urvi, Sweeney, Yvonne, Strizki, Julie, Hillier, Sharon L., Rohan, Lisa C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8955144/
https://www.ncbi.nlm.nih.gov/pubmed/35335526
http://dx.doi.org/10.3390/polym14061196

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8955144/
https://www.ncbi.nlm.nih.gov/pubmed/35335526
http://dx.doi.org/10.3390/polym14061196

Ejemplares similares