Disruption of Membrane Integrity as a Molecular Initiating Event Determines the Toxicity of Polyhexamethylene Guanidine Phosphate Depending on the Routes of Exposure

Polyhexamethylene guanidine phosphate (PHMG-P), a cationic biocide, is widely used in household products due to its strong bactericidal activity and low toxicity. However, it causes fatal lung damage when inhaled. In this study, we investigated why PHMG-P causes fatal lung injury when inhaled, and d...

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Detalles Bibliográficos
Autores principales: Song, Jeongah, Jung, Kyung-Jin, Yang, Mi-Jin, Kim, Woojin, Lee, Byoung-Seok, Choe, Seong-Kyu, Kim, Seong-Jin, Hwang, Jeong-Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8955148/
https://www.ncbi.nlm.nih.gov/pubmed/35328708
http://dx.doi.org/10.3390/ijms23063289

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8955148/
https://www.ncbi.nlm.nih.gov/pubmed/35328708
http://dx.doi.org/10.3390/ijms23063289

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