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Cyclodextrin Stabilized Freeze-Dried Silica/Chitosan Nanoparticles for Improved Terconazole Ocular Bioavailability

This research assesses the beneficial effects of loading terconazole, a poorly water-soluble antifungal drug in silica/chitosan nanoparticles (SCNs) for ocular delivery. Nanoparticles were fabricated by the simple mixing of tetraethyl ortho silicate (TEOS) and chitosan HCl as sources of silica and n...

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Detalles Bibliográficos
Autores principales: Zaghloul, Nada, El Hoffy, Nada M., Mahmoud, Azza A., Elkasabgy, Nermeen A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8955295/
https://www.ncbi.nlm.nih.gov/pubmed/35335847
http://dx.doi.org/10.3390/pharmaceutics14030470