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Nucleobase-Derived Nitrones: Synthesis and Antioxidant and Neuroprotective Activities in an In Vitro Model of Ischemia–Reperfusion

Herein, we report the synthesis, antioxidant, and neuroprotective properties of some nucleobase-derived nitrones named 9a–i. The neuroprotective properties of nitrones, 9a–i, were measured against an oxygen-glucose-deprivation in vitro ischemia model using human neuroblastoma SH-SY5Y cells. Our resu...

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Detalles Bibliográficos
Autores principales: Chamorro, Beatriz, Głowacka, Iwona E., Gotkowska, Joanna, Gulej, Rafał, Hadjipavlou-Litina, Dimitra, López-Muñoz, Francisco, Marco-Contelles, José, Piotrowska, Dorota G., Oset-Gasque, María Jesús
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8955307/
https://www.ncbi.nlm.nih.gov/pubmed/35328832
http://dx.doi.org/10.3390/ijms23063411