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Preclinical Evaluation of CAR T Cell Function: In Vitro and In Vivo Models

Immunotherapy using chimeric antigen receptor (CAR) T cells is a rapidly emerging modality that engineers T cells to redirect tumor-specific cytotoxicity. CAR T cells have been well characterized for their efficacy against B cell malignancies, and rigorously studied in other types of tumors. Preclin...

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Detalles Bibliográficos
Autores principales: Si, Xiaohui, Xiao, Lu, Brown, Christine E., Wang, Dongrui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8955360/
https://www.ncbi.nlm.nih.gov/pubmed/35328572
http://dx.doi.org/10.3390/ijms23063154