A Palmitic Acid-Conjugated, Peptide-Based pan-CoV Fusion Inhibitor Potently Inhibits Infection of SARS-CoV-2 Omicron and Other Variants of Concern

Our previous studies have shown that cholesterol-conjugated, peptide-based pan-coronavirus (CoV) fusion inhibitors can potently inhibit human CoV infection. However, only palmitic acid (C16)-based lipopeptide drugs have been tested clinically, suggesting that the development of C16-based lipopeptide...

Descripción completa

Detalles Bibliográficos
Autores principales: Lan, Qiaoshuai, Chan, Jasper Fuk-Woo, Xu, Wei, Wang, Lijue, Jiao, Fanke, Zhang, Guangxu, Pu, Jing, Zhou, Jie, Xia, Shuai, Lu, Lu, Yuen, Kwok-Yung, Jiang, Shibo, Wang, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8955410/
https://www.ncbi.nlm.nih.gov/pubmed/35336956
http://dx.doi.org/10.3390/v14030549

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8955410/
https://www.ncbi.nlm.nih.gov/pubmed/35336956
http://dx.doi.org/10.3390/v14030549

Ejemplares similares