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PRP4 Induces Epithelial–Mesenchymal Transition and Drug Resistance in Colon Cancer Cells via Activation of p53

Pre-mRNA processing factor 4B (PRP4) promotes pre-mRNA splicing and signal transduction. Recent studies have shown that PRP4 modulates the assembly of actin cytoskeleton in cancer cells and induces epithelial–mesenchymal transition (EMT) and drug resistance. PRP4 displays kinase domain-like cyclin-d...

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Detalles Bibliográficos
Autores principales: Islam, Salman Ul, Ahmed, Muhammad Bilal, Sonn, Jong-Kyung, Jin, Eun-Jung, Lee, Young-Sup
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8955441/
https://www.ncbi.nlm.nih.gov/pubmed/35328513
http://dx.doi.org/10.3390/ijms23063092