Fluorescence-Based Binding Characterization of Small Molecule Ligands Targeting CUG RNA Repeats

Pathogenic CUG and CCUG RNA repeats have been associated with myotonic dystrophy type 1 and 2 (DM1 and DM2), respectively. Identifying small molecules that can bind these RNA repeats is of great significance to develop potential therapeutics to treat these neurodegenerative diseases. Some studies ha...

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Detalles Bibliográficos
Autores principales: Chang, Zhihua, Zheng, Ya Ying, Mathivanan, Johnsi, Valsangkar, Vibhav A., Du, Jinxi, Abou-Elkhair, Reham A. I., Hassan, Abdalla E. A., Sheng, Jia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8955525/
https://www.ncbi.nlm.nih.gov/pubmed/35328743
http://dx.doi.org/10.3390/ijms23063321

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8955525/
https://www.ncbi.nlm.nih.gov/pubmed/35328743
http://dx.doi.org/10.3390/ijms23063321

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