Resveratrol Inhibited ADAM10 Mediated CXCL16-Cleavage and T-Cells Recruitment to Pancreatic β-Cells in Type 1 Diabetes Mellitus in Mice

Background: CXCL16 attracts T-cells to the site of inflammation after cleaving by A Disintegrin and Metalloproteinase (ADAM10). Aim: The current study explored the role of ADAM10/CXCL16/T-cell/NF-κB in the initiation of type 1 diabetes (T1D) with special reference to the potential protecting role of...

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Detalles Bibliográficos
Autores principales: Abdel-Bakky, Mohamed S., Alqasoumi, Abdulmajeed, Altowayan, Waleed M., Amin, Elham, Darwish, Mostafa A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8955623/
https://www.ncbi.nlm.nih.gov/pubmed/35335970
http://dx.doi.org/10.3390/pharmaceutics14030594

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8955623/
https://www.ncbi.nlm.nih.gov/pubmed/35335970
http://dx.doi.org/10.3390/pharmaceutics14030594

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