Three Birds, One Excipient: Development of an Improved pH, Isotonic, and Buffered Ketamine Formulation for Subcutaneous Injection

Subcutaneous (SC) ketamine has been found to be effective in pain management, though reports of injection site irritation and sterile abscesses exist with currently available ketamine HCl formulations. Such adverse SC reactions are commonly associated with low pH, high osmolality and/or high injecti...

Descripción completa

Detalles Bibliográficos
Autores principales: Wallach, Jason, Gamrat, James, Jauhola-Straight, Rebekah, Becker, Jeffrey, Eckrich, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8955626/
https://www.ncbi.nlm.nih.gov/pubmed/35335932
http://dx.doi.org/10.3390/pharmaceutics14030556

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8955626/
https://www.ncbi.nlm.nih.gov/pubmed/35335932
http://dx.doi.org/10.3390/pharmaceutics14030556

Ejemplares similares