The Poly-Histidine Tag H6 Mediates Structural and Functional Properties of Disintegrating, Protein-Releasing Inclusion Bodies

The coordination between histidine-rich peptides and divalent cations supports the formation of nano- and micro-scale protein biomaterials, including toxic and non-toxic functional amyloids, which can be adapted as drug delivery systems. Among them, inclusion bodies (IBs) formed in recombinant bacte...

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Detalles Bibliográficos
Autores principales: Sánchez, Julieta María, Carratalá, José Vicente, Serna, Naroa, Unzueta, Ugutz, Nolan, Verónica, Sánchez-Chardi, Alejandro, Voltà-Durán, Eric, López-Laguna, Hèctor, Ferrer-Miralles, Neus, Villaverde, Antonio, Vazquez, Esther
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8955739/
https://www.ncbi.nlm.nih.gov/pubmed/35335976
http://dx.doi.org/10.3390/pharmaceutics14030602

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8955739/
https://www.ncbi.nlm.nih.gov/pubmed/35335976
http://dx.doi.org/10.3390/pharmaceutics14030602

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