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To Enhance Mucus Penetration and Lung Absorption of Drug by Inhalable Nanocrystals-In-Microparticles

To effectively achieve the pulmonary delivery for curcumin (CN), novel inhalable mucus-penetrating nanocrystal-based microparticles (INMP) were designed. The D-Tocopherol acid polyethylene glycol 1000 succinate (TPGS) modified CN nanocrystals (CN-NS@TPGS) were prepared by high pressure homogenizatio...

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Detalles Bibliográficos
Autores principales: Huang, Guiting, Shuai, Shuyuan, Zhou, Weicheng, Chen, Yingchong, Shen, Baode, Yue, Pengfei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8955757/
https://www.ncbi.nlm.nih.gov/pubmed/35335914
http://dx.doi.org/10.3390/pharmaceutics14030538