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Quality by Design Assisted Optimization of a Chiral Capillary Electrokinetic Chromatographic Method for the Separation of Amlodipine Enantiomers Using Maltodextrin as Chiral Selector

Analytical-method development based on design of experiment has been applied for optimizing the enantioseparation of amlodipine by chiral capillary electrokinetic chromatography using maltodextrin as the chiral selector. The effect of different factors on the enantioresolution quality was screened....

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Detalles Bibliográficos
Autores principales: Ratih, Ratih, Wätzig, Hermann, Stein, Matthias Oliver, El Deeb, Sami
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8955793/
https://www.ncbi.nlm.nih.gov/pubmed/35337117
http://dx.doi.org/10.3390/ph15030319