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Drug Sensitivity of Vaccine-Derived Rubella Viruses and Quasispecies Evolution in Granulomatous Lesions of Two Ataxia-Telangiectasia Patients Treated with Nitazoxanide

A strong association between rubella virus (RuV) and chronic granulomas, in individuals with inborn errors of immunity, has been recently established. Both the RA27/3 vaccine and wild-type RuV strains were highly sensitive to a broad-spectrum antiviral drug, nitazoxanide (NTZ), in vitro. However, NT...

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Detalles Bibliográficos
Autores principales: Faisthalab, Raeesa, Suppiah, Suganthi, Dorsey, Morna, Sullivan, Kathleen E., Icenogle, Joseph, Perelygina, Ludmila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8955873/
https://www.ncbi.nlm.nih.gov/pubmed/35335662
http://dx.doi.org/10.3390/pathogens11030338