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Human Neurons Form Axon-Mediated Functional Connections with Human Cardiomyocytes in Compartmentalized Microfluidic Chip

The cardiac autonomic nervous system (cANS) regulates cardiac function by innervating cardiac tissue with axons, and cardiomyocytes (CMs) and neurons undergo comaturation during the heart innervation in embryogenesis. As cANS is essential for cardiac function, its dysfunctions might be fatal; theref...

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Detalles Bibliográficos
Autores principales: Häkli, Martta, Jäntti, Satu, Joki, Tiina, Sukki, Lassi, Tornberg, Kaisa, Aalto-Setälä, Katriina, Kallio, Pasi, Pekkanen-Mattila, Mari, Narkilahti, Susanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8955890/
https://www.ncbi.nlm.nih.gov/pubmed/35328569
http://dx.doi.org/10.3390/ijms23063148