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Human Neurons Form Axon-Mediated Functional Connections with Human Cardiomyocytes in Compartmentalized Microfluidic Chip
The cardiac autonomic nervous system (cANS) regulates cardiac function by innervating cardiac tissue with axons, and cardiomyocytes (CMs) and neurons undergo comaturation during the heart innervation in embryogenesis. As cANS is essential for cardiac function, its dysfunctions might be fatal; theref...
Autores principales: | Häkli, Martta, Jäntti, Satu, Joki, Tiina, Sukki, Lassi, Tornberg, Kaisa, Aalto-Setälä, Katriina, Kallio, Pasi, Pekkanen-Mattila, Mari, Narkilahti, Susanna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8955890/ https://www.ncbi.nlm.nih.gov/pubmed/35328569 http://dx.doi.org/10.3390/ijms23063148 |
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