Acanthaster planci Inhibits PCSK9 Gene Expression via Peroxisome Proliferator Response Element (PPRE) and Activation of MEK and PKC Signaling Pathways in Human Liver Cells

A constantly elevated level of low-density lipoprotein cholesterol (LDL-C) is mainly associated with the development of atherosclerosis. The use of statins as a treatment for reducing plasma LDL-C levels has led, in some cases, to adverse side effects, including a decrease in hepatic LDL receptor (L...

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Detalles Bibliográficos
Autores principales: Kamaruddin, Nurjannatul Naim, Mohd Din, Lukman Hakim, Jack, Allicia, Abdul Manan, Aina Farahiyah, Mohamad, Habsah, Tengku Muhammad, Tengku Sifzizul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8955981/
https://www.ncbi.nlm.nih.gov/pubmed/35337067
http://dx.doi.org/10.3390/ph15030269

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8955981/
https://www.ncbi.nlm.nih.gov/pubmed/35337067
http://dx.doi.org/10.3390/ph15030269

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