ABPP-HT*—Deep Meets Fast for Activity-Based Profiling of Deubiquitylating Enzymes Using Advanced DIA Mass Spectrometry Methods

Activity-based protein profiling (ABPP) uses a combination of activity-based chemical probes with mass spectrometry (MS) to selectively characterise a particular enzyme or enzyme class. ABPP has proven invaluable for profiling enzymatic inhibitors in drug discovery. When applied to cell extracts and...

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Detalles Bibliográficos
Autores principales: Jones, Hannah B. L., Heilig, Raphael, Davis, Simon, Fischer, Roman, Kessler, Benedikt M., Pinto-Fernández, Adán
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8955990/
https://www.ncbi.nlm.nih.gov/pubmed/35328685
http://dx.doi.org/10.3390/ijms23063263

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8955990/
https://www.ncbi.nlm.nih.gov/pubmed/35328685
http://dx.doi.org/10.3390/ijms23063263

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