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Functional analysis of polymorphisms at the S1/S2 site of SARS-CoV-2 spike protein

Several SARS-CoV-2 variants emerged that harbor mutations in the surface unit of the viral spike (S) protein that enhance infectivity and transmissibility. Here, we analyzed whether ten naturally-occurring mutations found within the extended loop harboring the S1/S2 cleavage site of the S protein, a...

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Detalles Bibliográficos
Autores principales: Arora, Prerna, Sidarovich, Anzhalika, Graichen, Luise, Hörnich, Bojan, Hahn, Alexander, Hoffmann, Markus, Pöhlmann, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8956166/
https://www.ncbi.nlm.nih.gov/pubmed/35333910
http://dx.doi.org/10.1371/journal.pone.0265453