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Individual cells generate their own self-reinforcing contact guidance cues through local matrix fiber remodeling

Directed cell migration arises from cells following a microenvironmental gradient (e.g. of a chemokine) or polarizing feature (e.g. a linear structure). However cells not only follow, but in many cases, also generate directionality cues by modifying their microenvironment. This bi-directional relati...

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Detalles Bibliográficos
Autores principales: Pamonag, Michael, Hinson, Abigail, Burton, Elisha J., Jafari, Nojan, Sales, Dominic, Babcock, Sarah, Basha, Rozlan, Hu, Xiaofeng, Kubow, Kristopher E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8956187/
https://www.ncbi.nlm.nih.gov/pubmed/35333902
http://dx.doi.org/10.1371/journal.pone.0265403