The mismatched nucleotides encoded in vaccinia virus flip-and-flop hairpin telomeres serve an essential role in virion maturation

Poxvirus genomes consist of a linear duplex DNA that ends in short inverted and complementary hairpin structures. These elements also encode loops and mismatches that likely serve a role in genome packaging and perhaps replication. We constructed mutant vaccinia viruses (VACV) where the native hairp...

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Detalles Bibliográficos
Autores principales: Shenouda, Mira M., Noyce, Ryan S., Lee, Stephen Z., Wang, Jun Li, Lin, Yi-Chan, Favis, Nicole A., Desaulniers, Megan A., Evans, David H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8956199/
https://www.ncbi.nlm.nih.gov/pubmed/35290406
http://dx.doi.org/10.1371/journal.ppat.1010392

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8956199/
https://www.ncbi.nlm.nih.gov/pubmed/35290406
http://dx.doi.org/10.1371/journal.ppat.1010392

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