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m(6)A mRNA modification maintains colonic epithelial cell homeostasis via NF-κB–mediated antiapoptotic pathway
Colonic mucosal barrier dysfunction is one of the major causes of inflammatory bowel disease (IBD). However, the mechanisms underlying mucosal barrier dysfunction are poorly understood. N(6)-methyladenosine (m(6)A) mRNA modification is an important modulator of epitranscriptional regulation of gene...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8956260/ https://www.ncbi.nlm.nih.gov/pubmed/35333576 http://dx.doi.org/10.1126/sciadv.abl5723 |