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m(6)A mRNA modification maintains colonic epithelial cell homeostasis via NF-κB–mediated antiapoptotic pathway

Colonic mucosal barrier dysfunction is one of the major causes of inflammatory bowel disease (IBD). However, the mechanisms underlying mucosal barrier dysfunction are poorly understood. N(6)-methyladenosine (m(6)A) mRNA modification is an important modulator of epitranscriptional regulation of gene...

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Detalles Bibliográficos
Autores principales: Zhang, Ting, Ding, Chenbo, Chen, Huifang, Zhao, Jun, Chen, Zhejun, Chen, Baiwen, Mao, Kaiqiong, Hao, Yajuan, Roulis, Manolis, Xu, Hao, Kluger, Yuval, Zou, Qiang, Ye, Youqiong, Zhan, Meixiao, Flavell, Richard A., Li, Hua-Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8956260/
https://www.ncbi.nlm.nih.gov/pubmed/35333576
http://dx.doi.org/10.1126/sciadv.abl5723